Hip fracture is one of the most dreaded hazards associated with aging.
Its incidence rises exponentially so that 90% of such fractures occur
after age 70.(39) It is estimated that 30% of older adults will have
experienced a hip fracture by age 90. With the aging of the population
, the prevalence of hip fracture will be increasing with its attendant
increase in disability and mortality of the affected population. Unli
ke the more common osteoporotic compression fractures of the spine, hi
p fracture is associated with a loss of independence in mobility and i
s a common cause of institutionalization. Among women suffering a hip
fracture, 15% to 25% will lose their independence in the first year af
ter the fracture.(38) Although mortality associated with this fracture
has been dramatically reduced over the past several decades by improv
ed surgical procedures, excess mortality is still between 7% and 20%.(
39) At age 50, a woman's chance of dying of a hip fracture is the same
as her chance of dying of breast cancer.(58) For those who survive, t
he economic burden of rehabilitation and extended care is of increasin
g concern as healthcare providers attempt to control healthcare costs.
Furthermore, there is some concern that the age-specific incidence of
hip fracture may also be increasing,(101,113) although more recent re
ports suggest that this may no longer be the case in the United States
or Scandinavia.(68) In this article, the authors explore the pathogen
esis of this age-related condition and the promising strategies that h
ave been developed to improve management of the patient with hip fract
ure and to prevent its occurrence.