REMARKABLE SALT EFFECTS IN THE HIGHLY ENHANCED ENANTIOSELECTIVE HYDROLYSIS OF AMINO-ACID ESTERS WITH THE ACTIVE TRIPEPTIDE IN THE VESICULARSYSTEM

Authors
GOTO K IMAMURA C YAMAMOTO S MATSUMOTO Y UEOKA R
Citation
K. Goto et al., REMARKABLE SALT EFFECTS IN THE HIGHLY ENHANCED ENANTIOSELECTIVE HYDROLYSIS OF AMINO-ACID ESTERS WITH THE ACTIVE TRIPEPTIDE IN THE VESICULARSYSTEM, Chemistry Letters, (11), 1994, pp. 2081-2084
Citations number
6
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
11
Year of publication
1994
Pages
2081 - 2084
Database
ISI
SICI code
0366-7022(1994):11<2081:RSEITH>2.0.ZU;2-S
Abstract
The remarkably high enantioselectivity (k(L) (a,obsd)/k(D) (a,obsd) = 67) was attained along with the large rate-enhancement of the L-form s ubstrate for the hydrolytic cleavage of N-dodecanoyl-D(L)-Phe-PNP by c ontrolling the ionic strength ([KCl] = 0.03 M, 1M = 1 mol dm(-3)) in t he vesicular system.