THE TRYPANOCIDAL EFFECT OF CANNABIS-SATIVA CONSTITUENTS IN EXPERIMENTAL ANIMAL TRYPANOSOMIASIS

Authors
NOK AJ IBRAHIM S AROWOSAFE S LONGDET I AMBROSE A ONYENEKWE PC WHONG CZ
Citation
Aj. Nok et al., THE TRYPANOCIDAL EFFECT OF CANNABIS-SATIVA CONSTITUENTS IN EXPERIMENTAL ANIMAL TRYPANOSOMIASIS, Veterinary and human toxicology, 36(6), 1994, pp. 522-524
Citations number
10
Categorie Soggetti
Toxicology,"Veterinary Sciences
Journal title
Veterinary and human toxicology → ACNP
ISSN journal
01456296
Volume
36
Issue
6
Year of publication
1994
Pages
522 - 524
Database
ISI
SICI code
0145-6296(1994)36:6<522:TTEOCC>2.0.ZU;2-R
Abstract
The effect of Cannabis sativa on trypanosome-infected rats was examine d. An aqueous extract of the seeds administered at a dose of 50 mg/kg/ d cured animals infected with Trypanosome brucei brucei of blood strea m parasites. Six fractions eluted from the crude extract by column chr omatography were assessed for trypanocidal properties. Of these, only 2 fractions retained trypanocidal activity by curing mice infected wit h T brucei brucei.