Background. - Incidence of aortic thromboses in the neonatal period is
significantly increased after umbilicar artery catheterization. Popul
ation and methods. - Fourty neonates (GA: 34.7 +/- 7.2 wks and birth w
eight: 2377 +/- 786 g) were prospectively studied in order to assess f
requency and natural history of aortic thromboses due to umbilical art
ery catheterization, Investigation was based on serial real-time ultra
sonography (2.3 times/week). Presence of aortic thrombus was correlate
d with the existence of clinical complications and the results of biol
ogical findings (prothrombin and fibrinogen levels; hematocrit) and pl
atelet number. Results. - Aortic thrombosis was found in sin patients
(15%); it was clinically asymptomatic in two (5%). A vascular wall-fix
ed catheter was shown in ten infants (25%); this finding was associate
d with thrombosis in five cases and preceded thrombosis in one other.
The presence of thrombus and/or abnormal position of the catheter was
not corre- lated with gestational age, birth weight, duration of cathe
terization, blood hemostasis and results of bacteriological cultures o
f the tip of the catheter. Conclusions. - Ultrasonographic control mus
t be repeated after umbilical artery catheterization. It permits evalu
ation of renal flux and can lead to removal of catheter and/or peculia
r therapeutic measures.