ADVERSE CUTANEOUS REACTIONS TO CHEMOTHERAPEUTIC-AGENTS AND CYTOKINE THERAPY

This article reviews the adverse cutaneous reactions to antineoplastic chemotherapeutic agents and cytokine therapy. The article details spe cific reactions such as acral erythemas and Rushing reactions. It also discusses nonspecific reactions with specific histological features s uch as neutrophilic eccrine hidradenitis and syringosquamous metaplasi a. The wide variety of cutaneous reactions to cytokine therapy such as from recombinant interleukins and the colony stimulating factors are reviewed.