A CDNA ENCODES THE DROSOPHILA HOMOLOG OF YEAST 60S RIBOSOMAL-PROTEIN YL43

We describe the nucleotide sequence of a cDNA clone isolated from Dros ophila Kc cells which encodes an amino acid sequence homologous to a 6 0S ribosomal protein from yeast (YL43) and rat (p23). The DL43 cDNA is 320 nucleotides in length and predicts a protein of 76 amino acids an d a calculated molecular mass of 8.9 kiloDaltons. Northern blot analys is demonstrates the presence of the DL43 transcript under both control (25 degrees C) and heat shock (37 degrees C) conditions. The Drosophi la protein shares an 86% identity over the first 22 amino acids with t he yeast YL43 protein and a 60% identity over the entire length of the partial sequence available for this protein.