E. Ejlersen et al., A COMPARISON BETWEEN PREINCISIONAL AND POSTINCISIONAL LIDOCAINE INFILTRATION AND POSTOPERATIVE PAIN, Anesthesia and analgesia, 74(4), 1992, pp. 495-498
We conducted a randomized, double-blind trial to compare the efficacy
of preincisional and postincisional wound infiltration with 1% lidocai
ne (40 mL) on the postoperative pain of 37 patients scheduled for elec
tive inguinal herniotomy. The demand for additional postoperative anal
gesics occurred earlier in those who received lidocaine infiltration a
fter incision (165 min) than in those who received preincisional lidoc
aine (225 min, P < 0.05). The preincisional lidocaine infiltration gro
up also had fewer patients requiring supplemental analgesics (58%) tha
n the postincisional group (94%) (P < 0.05). We conclude that preincis
ional infiltration of the surgical wound with lidocaine is a more effe
ctive method of providing postoperative analgesia than is postincision
al infiltration.