CHLORAL HYDRATE TOXICITY IN A TERM INFANT

Authors
ANYEBUNO MA ROSENFELD CR
Citation
Ma. Anyebuno et Cr. Rosenfeld, CHLORAL HYDRATE TOXICITY IN A TERM INFANT, Developmental pharmacology and therapeutics, 17(1-2), 1991, pp. 116-120
Citations number
19
Journal title
Developmental pharmacology and therapeutics → ACNP
ISSN journal
03798305
Volume
17
Issue
1-2
Year of publication
1991
Pages
116 - 120
Database
ISI
SICI code
0379-8305(1991)17:1-2<116:CHTIAT>2.0.ZU;2-K
Abstract
Chlorate hydrate is commonly used for neonatal sedation, but blood lev els are infrequently monitored, reflecting an underemphasis of acute t oxic effects. This report describes a case of chloral hydrate toxicity in a term infant with cardiac, renal, neurologic, bladder and gastroi ntestinal dysfunction. The effects of exchange transfusion are describ ed as well as pharmacokinetics.