This survey covers analysis, occurrence, and formation of tryptophan-d
erived compounds in food and edible plants as well, as dietary and met
abolic aspects of tryptophan derivatives. After summarizing biosynthes
is and metabolism of tryptophan, attention is focused on products obta
ined by oxidative degradation reactions, compounds derived from the Ma
illard reaction, tetrahydro-beta-carbolines, and harman derivatives. I
n addition, formation of heterocyclic aromatic amines and relevance of
tryptophan contaminants for the outbreak of the eosinophilia-myalgia
syndrome (EMS) are reviewed.