EFFECTS OF ALPRAZOLAM ON THE DEVELOPMENT OF MTV-INDUCED MAMMARY-TUMORS IN FEMALE MICE UNDER STRESS

Authors
FREIREGARABAL M NUNEZ MJ BALBOA JL SUAREZ JA BELMONTE A
Citation
M. Freiregarabal et al., EFFECTS OF ALPRAZOLAM ON THE DEVELOPMENT OF MTV-INDUCED MAMMARY-TUMORS IN FEMALE MICE UNDER STRESS, Cancer letters, 62(3), 1992, pp. 185-189
Citations number
50
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
62
Issue
3
Year of publication
1992
Pages
185 - 189
Database
ISI
SICI code
0304-3835(1992)62:3<185:EOAOTD>2.0.ZU;2-E
Abstract
Female C3H/He mice carrying the mammary tumor virus (MTV) were monitor ed for mammary tumor incidence and latent periods while subjected to a daily intraperitoneal (i.p.) injection of placebo or alprazolam (1 mg /kg per day). Although all of the mice were potential candidates for M TV-induced breast cancer, those injected with alprazolam were partiall y protected against adverse effects of stress induced by the daily adm inistration of placebo.