A case of infectious mononucleosis (IM) which, on computed tomography
(CT) scan, mimicked the morphologic features of lymphoma is reported.
The CT findings in this case include generalized lymphadenopathy, sple
nomegaly, and focal low-attenuation splenic lesions in a fifty-three y
ear old woman; these findings have not previously been described in pa
tients with IM. This is most likely because IM is usually a clinical d
iagnosis confirmed by serologic testing. Imaging modalities such as CT
scan have not routinely been utilized to support this diagnosis.