THE MSH ACTH ANALOG ORG-2766 IN ANXIETY DISORDERS/

Citation
Ja. Denboer et al., THE MSH ACTH ANALOG ORG-2766 IN ANXIETY DISORDERS/, Peptides, 13(1), 1992, pp. 109-112
Citations number
23
Journal title
ISSN journal
01969781
Volume
13
Issue
1
Year of publication
1992
Pages
109 - 112
Database
ISI
SICI code
0196-9781(1992)13:1<109:TMAAOI>2.0.ZU;2-#
Abstract
The anxiolytic effects of the MSH/ACTH analog ORG 2766 were assessed i n three different groups of patients with an anxiety disorder: panic d isorder, generalized anxiety and social phobia. Patients were treated with capsules containing 20 mg ORG 2766 or placebo and received 4 caps ules daily for six weeks. A slight reduction on the Hamilton Anxiety S cale was found after ORG 2766 treatment in the panic disorder patients . while the peptide did not affect the number of panic attacks in thes e patients. In the other two patient groups no anxiolytic effect of OR G 2766 was observed.