The anxiolytic effects of the MSH/ACTH analog ORG 2766 were assessed i
n three different groups of patients with an anxiety disorder: panic d
isorder, generalized anxiety and social phobia. Patients were treated
with capsules containing 20 mg ORG 2766 or placebo and received 4 caps
ules daily for six weeks. A slight reduction on the Hamilton Anxiety S
cale was found after ORG 2766 treatment in the panic disorder patients
. while the peptide did not affect the number of panic attacks in thes
e patients. In the other two patient groups no anxiolytic effect of OR
G 2766 was observed.