Sr. Dolgin et al., DIFFERENT OPTIONS FOR TREATMENT OF INVERTING PAPILLOMA OF THE NOSE AND PARANASAL SINUSES - A REPORT OF 41 CASES, The Laryngoscope, 102(3), 1992, pp. 231-236
Forty-two cases of inverting papilloma of the nose and paranasal sinus
es were reviewed from 1972 to 1989. Forty-one patients underwent surgi
cal excision. Of those patients followed up for at least 6 months, lat
eral rhinotomy was performed in 14 patients and midfacial degloving in
9 patients. The recurrence rates were 29% and 22%, respectively. The
other 10 patients underwent excision through an external ethmoidectomy
, Caldwell-Luc operation, or intranasal approach. There were five pati
ents (12%) diagnosed with squamous cell carcinoma associated with inve
rting papilloma. The correlation of malignancy with proptosis, visual
changes, infraorbital hypesthesia, and skull base involvement on prese
nting symptomatology is noted. Inverting papilloma is a benign neoplas
tic lesion that shows variable aggressiveness. A computed tomography (
CT) scan evaluation is very important for the work-up. An aggressive w
ide surgical excision is best performed through an open approach. The
approach for surgical removal should be based on the location and exte
nsion of the lesion. A graduating approach from a lesser to a more maj
or excision is advocated even though a risk exists of having to reoper
ate in about one fifth of the patients who experience a recurrence. A
secondary surgical excision, even with craniofacial resection, is esse
ntial to eradicate disease in cases of recurrence. Close follow-up is
necessary. Further surgery may be indicated. Post-operative radiation
therapy is recommended if malignancy is indeed present.