Pentastomids are a class of crustacean endoparasites that, as adults,
parasitize the respiratory tract of vertebrates. They have evolved som
e unique strategies for long-term survival in vertebrate lungs which a
ppear to be equally useful in thwarting inflammatory responses in the
tissues of intermediate hosts. In this article, John Riley outlines th
e possible biological roles and immunological relevance of pentastomid
excretory/secretory (E/S) products that may be important to parasite
survival.