CYCLOPHOSPHAMIDE FOR SIGMOID STENOSIS IN POLYARTERITIS-NODOSA

Objective: Treatment of ischaemic sigmoid stenosis in polyarteritis no dosa. Design: A single patient case report, describing pre- and post-t herapy symptoms. Setting: Department of internal medicine in a univers ity hospital Patient: A 43-year-old woman with an 8-year history of po lyarteritis nodosa and a recent sigmoid stenosis, which on angiographi c findings was suggestive of an ischaemic process, that was resistant to corticosteriods. Interventions: The patient received six montly i.v . pulses of cyclophosphamide. Outcome: Clinical and radiological signs disappeared after cyclophosamide pulses and oral prednisone dose coul d be reduced. Conclusions: This colonic localized form of polyarteriti s nodosa was sensitive to cyclophosphamide.