There has been great concern in the past regarding the possible fetal
infection and teratogenicity from Lyme disease contracted during pregn
ancy because of the similarities of disease caused by Borrelia burgdor
feri to syphilis. Although the initial retrospective case reports were
alarming, more recent prospective data have been reassuring. This art
icle reviews the evidence that currently supports the assurance of the
benign nature of this infection with respect to the fetus.