This article reviews the parasitology of malaria, epidemiology in preg
nancy, pathogenesis of increased susceptibility to infection in pregna
ncy, the effect of pregnancy on the clinical manifestations of malaria
, the effect of malaria on perinatal outcomes, the safety of antimalar
ial agents during pregnancy, the role of chemoprophylaxis for inhabita
nts and travelers to endemic areas, and treatment of clinical malarial
infections during pregnancy.