We analyzed data from a survey of occupational factors and pregnancy o
utcome to examine the effects of cigarette, alcohol, and coffee consum
ption on pregnancy outcome. Clear and statistically significant associ
ations were found between cigarette and alcohol consumption and sponta
neous abortion. There was a weaker but statistically significant assoc
iation with coffee consumption: If the associations were casual, 11% o
f the spontaneous abortions could be attributed to smoking, 5% to alco
hol, and 2% to coffee.