Oak poisoning occurred in crossbred cattle due to eating immature tend
er oak (Quercus incana) leaves. Mortality was 70%. The animals exhibit
ed anorexia, severe constipation and brisket edema. The feces were har
d, pelleted and coated with blood and mucous. Significant reductions i
n blood hemoglobin and mean corpuscular hemoglobin, and significant el
evations in serum bilirubin were observed. Serum urea nitrogen and cre
atinine were greatly increased. There was bilirubinuria, proteinuria,
hypoproteinemia and hypocalcemia, and greatly increased activities of
serum aspartate aminotransferase, lactate dehydrogenase and alkaline p
hosphatase. The levels of tannins and condensed tannins were 97.7 mg t
annic acid equivalent and 5.8 mg catechin equivalent/g of dry leaves.
There was extensive nephro- and hepatotoxicity in the affected cattle
due to hydrolysable tannins and simple phenols in the oak leaves.