F. Guermazi et al., THERAPEUTIC EFFICIENCY OF AUTONOMOUS NODULE OF THE THYROID AND TOXIC MULTINODULAR GOITER WITH I-131 - ABOUT 59 CASES, Annales d'Endocrinologie, 52(5), 1991, pp. 323-326
Our study dealt with 81 patients treated by iodine 131 for autonomous
goiter. We have followed 59 patients during about a year. The global t
herapeutic efficiency is of 73% and the risk of hypothyroidism is very
weak. The administration of a high activity (> 15 mCi) of iodine allo
ws to get a faster recovery, a better therapeutic efficiency and permi
ts to reduce the number of cures (therefore, to reduce the irradiation
of the patient), nevertheless, the risk of hypothyroidism is very sli
ght. The advantages of metabolic radiotherapy (low cost, facility of a
dministration, efficiency) make it preferable to surgery, above all wi
th patients that are more than 40 years old, for whom the radiation ri
sk is practically null (hereditary diseases, cancer).