ANSA STEROIDS - NEWS ON A NOVEL TYPE OF COMPOUND

Authors
WINTERFELDT E
Citation
E. Winterfeldt, ANSA STEROIDS - NEWS ON A NOVEL TYPE OF COMPOUND, Chimia, 47(3), 1993, pp. 39-45
Citations number
8
Journal title
Chimia → ACNP
ISSN journal
00094293
Volume
47
Issue
3
Year of publication
1993
Pages
39 - 45
Database
ISI
SICI code
0009-4293(1993)47:3<39:AS-NOA>2.0.ZU;2-C
Abstract
In this report we communicate recent results from our investigations w ith ansa-steroids. Following a detailed inspection of the stereoselect ivity of epoxidations, a highly regioselective Baeyer-Villiger oxidati on to form lactones was developed. After deciding on the proper starti ng material, we were also quite successful with the Birch reduction of the aromatic ring to generate cyclohexadienes. Efforts to open the fi ve-membered ring via autoxidation and fragmentation met with failure.