O. Saintjean et al., DEMENTIA AND ACUTE ASSOCIATED DISEASES IN ELDERLY SUBJECTS - A STUDY OF 100 PATIENTS AGED OVER 75 IN AN INTERNAL-MEDICINE AND GERIATRIC UNIT, La Revue de medecine interne, 14(3), 1993, pp. 182-188
Elderly people with dementia are admitted in ever increasing number to
Internal Medicine units for exploration of dementia and treatment of
intercurrent diseases. The purpose of this prospective study of 100 de
mential subjects aged 75 or more (mean : 85.3 +/- 5.4 years) was to di
scover the cause of dementia, to investigate the associated diseases a
nd to evaluate the effects of treatment of these pathologies on the pa
tients' cognitive performance. The mean duration of stay in hospital w
as 25.5 +/- 14.5 days (extreme : 6-100 days) ; 69 returned home, 17 we
re institutionalized and 14 died. Dementia was degenerative and of the
Alzheimer type (73 %) with vascular lesions (24 %) associated with br
ain tumours (2 %) or normal-pressure hydrocephalus (1 %). On average,
2 pathologies were associated with Alzheimer's dementia and 3.5 with d
ementia cum vascular brain lesions. Repeated evaluation of cognitive p
erformance was carried out using Folster's Mini Mental Status (MMS), a
global evaluation test. It showed that 18 % of the patients were sign
ificantly improved while the other diseases were being treated. The hy
pothesis of regressive confusional elements superimposed on dementia i
s accepted by the authors as it fits the model of geriatric multipatho
logy morbidity. Since there is no specific treatment for most types of
dementia, particular attention must be paid to associated diseases li
kely to aggravate the clinical expression of dementia.