CARNEY COMPLEX WITH PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE AND SPOTTY PIGMENTATIONS

Carney's complex is composed of myxoma, spotty pigmentation and endocr ine overactivity. A 27-year-old male was diagnosed to have Carney's co mplex on the basis of intense spotty pigmentations on his face, soles and palms, and bilateral adrenal nodular hyperplasia on computed tomog raphy scanning (CT) and magnetic resonance imaging (MRI). Total bilate ral adrenectomy was done; histological findings were compatible with p rimary pigmented adrenocortical disease (PPNAD). Recently, his sister and one of his brothers were suspected to have Carney's complex with P PNAD. We report the first familial case of Carney's complex with PPNAD and spotty pigmentations in Japan.