The field of pharmacoeconomics is of growing interest to everyone from
government policy makers to medical staff and administrators at hospi
tals and other managed care settings. This article reviews basic termi
nology and methodologic issues related to using pharmacoeconomics to e
valuate drugs and services. Economic evaluation tools such as cost-ben
efit analysis, cost-effectiveness analysis, cost-utility analysis, and
cost-minimization analysis are described. The challenge for all clini
cians is to use these economic evaluation tools to optimize the benefi
t-to-cost ratio and resultant positive outcome of programs, services,
treatments, or other interventions for the patient, the institution, a
nd society.