PERINEURONAL SATELLITOSIS IN THE HUMAN HIPPOCAMPAL-FORMATION

A previously unreported example of perineuronal satellitosis in the me dial CA1 and adjacent subiculum in the human hippocampal formation is described. This phenomenon is characterized by a clustering of glial c ells in relation to the perikarya of a subpopulation of neurons in the deep pyramidal layer and around most neurons scattered in the stratum oriens and subcortical white matter. Most of the perineuronal satelli te glia were identified as oligodendrocytes based on their nuclear chr omatin patterns and antigenic properties. Satellite oligodendrocytes w ere mostly of the medium dense variety. A type of satellite glia with nuclear features of the dark oligodendrocyte could not be identified u nequivocally using the antigenic criteria employed in this study.