OXIDATIVE REARRANGEMENTS OF ALKYL SUBSTITUTED ISOQUINOLINE ENAMIDES TO 1-HYDROXYMETHYLDIHYDROISOQUINOLINE DERIVATIVES

Authors
LENZ GR LESSOR RA RAFALKO PW KOSARYCH Z
Citation
Gr. Lenz et al., OXIDATIVE REARRANGEMENTS OF ALKYL SUBSTITUTED ISOQUINOLINE ENAMIDES TO 1-HYDROXYMETHYLDIHYDROISOQUINOLINE DERIVATIVES, Journal of the Chemical Society. Perkin transactions. I, (7), 1993, pp. 745-746
Citations number
8
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
7
Year of publication
1993
Pages
745 - 746
Database
ISI
SICI code
0300-922X(1993):7<745:OROASI>2.0.ZU;2-3
Abstract
Oxidation of disubstituted 1 -methylenedihydroisoquinoline enamides wi th lead tetraacetate results in a novel N-->C oxidative rearrangement whereby esters of disubstituted 1-hydroxymethyl-3,4-dihydroisoquinolin e are formed. An X-ray crystallographic structural determination for b enzoyloxy)-1-methylethyl]-3,4-dihydroisoquinoline 4 is described.