The aim of our study was to establish whether ultrasonography can be p
roposed as the main diagnostic technique for the follow-up of soft tis
sue sarcoma (STS). In 26 patients with previous history of STS, a sono
graphic examination was carried out using a 5 MHz linear transducer to
identify early local recurrences. Sonography was performed every 3 mo
nths and a computed tomographic (CT) control was made when the sonogra
m showed findings strongly suggestive of recurrence. STS recurrences w
ere detected by sonography in 20 of 26 patients (77%) and were confirm
ed by histologic examination. In six cases, sonographic results were u
ncertain and in three of these the recurrence was ascertained by biops
y. CT scan provided a correct diagnosis in 16 patients (61.5%) and onl
y in cases with lesions greater than 5 cm in diameter. From our experi
ence we conclude that high frequency sonography is a most accurate non
invasive approach in early detection of STS recurrences. CT plays an i
mportant role in the cases amenable to surgery treatment and is recomm
ended to obtain a better assessment of anatomic connection between tum
or and adjacent structures.