Nine gastric adenocarcinomas containing endocrine cells were retrospec
tively studied to evaluate anatomo-clinical and immunohistochemical fe
atures, and the out-come of the patients. These gastric tumors were bu
lky with frequently lymph node metastasis. The immunohistochemical ana
lysis had shown that all tumors contain EC cells, two tumors D cells,
one tumor PP cells, but neither G cells nor A cells were detected. Fiv
e-years survival rate of these gastric tumors was slightly but not sig
nificantly increased as compared to usual adenocarcinomas (45.5 % vs 3
6.5 %). However, one can raise the question of possible control of loc
al hormonal secretions on tumoral growth, particularly the antitrophic
part of the somalostatin.