HUMAN INTERFERON-ALPHA FAILS TO INHIBIT THE DEVELOPMENT OF BABESIA-BIGEMINA AND ANAPLASMA-MARGINALE INFECTIONS IN CATTLE

Authors
ORINDA GO WRIGHT IG LEATCH G YOUNG AS
Citation
Go. Orinda et al., HUMAN INTERFERON-ALPHA FAILS TO INHIBIT THE DEVELOPMENT OF BABESIA-BIGEMINA AND ANAPLASMA-MARGINALE INFECTIONS IN CATTLE, Veterinary parasitology, 47(1-2), 1993, pp. 149-155
Citations number
28
Journal title
Veterinary parasitology → ACNP
ISSN journal
03044017
Volume
47
Issue
1-2
Year of publication
1993
Pages
149 - 155
Database
ISI
SICI code
0304-4017(1993)47:1-2<149:HIFTIT>2.0.ZU;2-R
Abstract
Studies were undertaken to determine whether human interferon alpha (H uIFN-alpha) administered orally could inhibit the development of clini cal disease caused by the intraerythrocytic protozoan Babesia bigemina and the intraerythrocytic rickettsia Anaplasma marginale in cattle. H uIFN-alpha did not inhibit intraerythrocytic multiplication of either of the two parasites, suggesting that there is no role for HuIFN-alpha administered orally in the control of these pathogens.