CONTRAST AGENT OVERDOSE CAUSING BRAIN RETENTION OF CONTRAST, SEIZURES, AND PARKINSONISM

A patient received an overdose of intravascular contrast medium and ex perienced protracted seizures associated with radiographic evidence of prolonged retention of the contrast agent in the cerebral cortex, bas al ganglia, and thalami. This is only the second report and the first survivor of a similar neurologic syndrome occurring in a patient after contrast agent overdose. After the seizures resolved, there was a tra nsient period of parkinsonism probably due to the toxic effect of cont rast on the basal ganglia.