COMPARISON OF THE ACCEPTABILITY OF THE VENTOLIN METERED-DOSE INHALER AND THE BRICANYL TURBUHALER

One hundred fifty-nine asthmatic patients aged 19 to 76 years complete d an open crossover-designed study comparing the acceptability of the Bricanyl Turbuhaler (BTH) and the Ventolin metered-dose inhaler (VMDI) . The doses given were presumed to be equiactive. Each treatment perio d lasted for 14 days. Patients registered morning and evening peak exp iratory flow rate (PEFR) before and five minutes after medication. Ast hma symptoms as well as adverse events were registered on diary cards. After each study period a questionnaire containing acceptability ques tions was completed. At the end of the study the patients indicated th eir preference for one of the two treatments. The two treatments were equal concerning bronchodilation and asthma symptoms. There was an ove rall preference for the Bricanyl Turbuhaler.