CERVICAL-CARCINOMA IN YOUNG-PATIENTS - CLINICAL AND PATHOLOGICAL VARIABLES

Twenty-five (10.2%) out of 243 untreated patients with invasive cervic al carcinoma were 35 years old or younger. When matching the clinical and pathological variables between the younger and the older women, th e former were characterized by a higher rate of Stage IB disease (P = 0.10), G3 and G4 tumors (P = 0.25), bulky lesions (P = 0.05) and node metastases (P = 0.50). In spite of this poorer pathological profile, b oth the 5-year disease-free survival rate (75%) and survival according to stage of the younger women were similar to those reported in large r series, regardless of the patients' age. No modification of the stan dard therapy is therefore required in younger patients.