Numerous uncontrolled trials have suggested that laparoscopic cholecys
tectomy (LC) is a major improvement over open cholecystectomy (OC). In
an effort to objectively document the benefits of LC, two Canadian st
udies are reviewed. The first is a matched time series based on prospe
ctive data from a single surgeon's practice in which patients are clos
ely matched for baseline characteristics. The groups consist of 121 pa
tients from each of 3 time periods: 1989, prior to the introduction of
LC; 1990, when LC was being introduced; and 1991, when LC had become
the preferred method of cholecystectomy. The second study is a randomi
zed trial, in which LC is compared with mini-cholecystectomy. In both
studies, the superior efficacy of LC is demonstrated with respect to t
he duration of hospitalization and the duration of postoperative conva
lescence. The incidence of complications as well as their severity is
also less in LC patients. Although quality of life improves after any
type of cholecystectomy, LC patients improve faster and seem to accept
the operation better. These studies support the widespread dispersion
of LC in Canada, although comparative efficacy with nonsurgical alter
natives has not been addressed.