Noninvasive or minimally invasive techniques for the treatment of bili
ary stones have been significantly advanced in the past two decades. T
he least invasive, extracorporeal shock-wave lithotripsy, continues to
be used successfully, not only at its earliest reported site of use i
n Munich, Germany, but also in numerous other centers in the world. Li
thotriptors that utilize a spark gap electrode or other source of ener
gy to generate sound waves and imaging by radiographic and ultrasonogr
aphic targeting of stones have proved to be effective in fragmenting b
iliary stones (90% to 95%) that are too large or otherwise inaccessibl
e to removal by endoscopic papillotomy. Stone clearance (53% to 90%) m
ay require successive treatments and the removal of debris by transend
oscopic or surgical means. The mortality is low (0.5%), and the posttr
eatment course is relatively uncomplicated in an elderly, high-risk gr
oup of patients.