G. Nuzzi et al., VITREOUS FLUOROPHOTOMETRY AND CHANGES IN BLOOD-RETINAL BARRIER PERMEABILITY INDUCED BY BENDAZAC LYSINE, Acta ophthalmologica Scandinavica, 75(1), 1997, pp. 41-43
Vitreous fluorophotometry was used to investigate the effect of Bendaz
ac lysine on the blood retinal barrier in 12 insulin-dependent diabeti
cs with mild background retinopathy. The study was a randomized, doubl
e blind, cross-over trial, drug versus Placebo. Each treatment period
was of 4 months. The vitreous penetration coefficient was reduced by 2
1% (95% c.i. 12, 30; p = 0.001) by treatment with respect to Placebo.