NEW PASPALININE DERIVATIVES WITH ANTIINSECTAN ACTIVITY FROM THE SCLEROTIA OF ASPERGILLUS-NOMIUS

Authors
STAUB GM GLOER KB GLOER JB WICKLOW DT DOWD PF
Citation
Gm. Staub et al., NEW PASPALININE DERIVATIVES WITH ANTIINSECTAN ACTIVITY FROM THE SCLEROTIA OF ASPERGILLUS-NOMIUS, Tetrahedron letters, 34(16), 1993, pp. 2569-2572
Citations number
12
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
16
Year of publication
1993
Pages
2569 - 2572
Database
ISI
SICI code
0040-4039(1993)34:16<2569:NPDWAA>2.0.ZU;2-#
Abstract
14-Hydroxypaspalinine (3) and 14-(N,N-Dimethyl-L-valyloxy)paspalinine (4) have been isolated from the sclerotia of Aspergillus nomius, and i dentified by analysis of 2D NMR data. Both compounds cause ca. 90% red uction in weight gain in assays against the com earworm Helicoverpa ze a at the 100 ppm (dry weight) dietary level. Paspalinine causes no eff ect at this concentration.