SCALE-INVARIANT SPATIAL PATTERNS IN GENOME ORGANIZATION

Authors
Citation
Md. Purugganan, SCALE-INVARIANT SPATIAL PATTERNS IN GENOME ORGANIZATION, Physics letters. A, 175(3-4), 1993, pp. 252-256
Citations number
34
Journal title
ISSN journal
03759601
Volume
175
Issue
3-4
Year of publication
1993
Pages
252 - 256
Database
ISI
SICI code
0375-9601(1993)175:3-4<252:SSPIGO>2.0.ZU;2-7
Abstract
Eukaryotic genomes are characterized by coding regions interspersed wi thin non-coding sequences, creating irregular dispersal patterns. Frac tal analysis was applied to the study of this dispersed organization o f eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regi me with fractal dimensions ranging from 0.21 +/- 0.02 to 0.84 +/- 0.02 . Fractal scaling provides clues to the origin and evolution of sequen ce patterns within genomes, and provides us with tools necessary to ch aracterize such patterns in detail.