The new alkaloids neolaugerine, isoneolaugerine and 15-hydroxyneolauge
rine, possessing an original oxindole skeleton, have been isolated fro
m the root bark of Neolaugeria resinosa. Their structures and stereoch
emistry were established by chemical and spectroscopic methods, includ
ing mass spectrometry, H-1, C-13, 2D and NOE NMR experiments.