EBURNANE-14-SPIRO HETEROCYCLES - SYNTHESIS AND STEREOSTRUCTURE DETERMINATION BY NMR-SPECTROSCOPY

Authors
NEMES A SOHAR P KOVESDI I CZIBULA L CSEHI A KREIDL J
Citation
A. Nemes et al., EBURNANE-14-SPIRO HETEROCYCLES - SYNTHESIS AND STEREOSTRUCTURE DETERMINATION BY NMR-SPECTROSCOPY, Magnetic resonance in chemistry, 31(4), 1993, pp. 409-415
Citations number
15
Journal title
Magnetic resonance in chemistry → ACNP
ISSN journal
07491581
Volume
31
Issue
4
Year of publication
1993
Pages
409 - 415
Database
ISI
SICI code
0749-1581(1993)31:4<409:EH-SAS>2.0.ZU;2-Z
Abstract
New spiroheterocyclic systems, eburnane-14-spiro-5'-oxazolidinedione, eburnane-14-spiro-4'-imidazolidinedione and related compounds were pre pared by reacting vincamine stereoisomers or 14-desoxy-14-aminovincami nes with alkyl isocyanates. Stereostructures of the new compounds were proved by H-1 and C-13 NMR spectroscopy, including DR, DNOE, DEPT and 2D HSC measurements.