HPLC SEPARATION OF CHIRAL BENZO-1,4-DIAZEPINES

Citation
T. Jira et al., HPLC SEPARATION OF CHIRAL BENZO-1,4-DIAZEPINES, Die Pharmazie, 48(3), 1993, pp. 196-198
Citations number
13
Journal title
ISSN journal
00317144
Volume
48
Issue
3
Year of publication
1993
Pages
196 - 198
Database
ISI
SICI code
0031-7144(1993)48:3<196:HSOCB>2.0.ZU;2-G
Abstract
Cyclodextrins as chiral stationary phases (CSP) are useful for chromat ographic separations of racemic analytes, which are able for enantiose lective interactions with the CSP. Studies in this work are reported a nalytical separations of various benzo-1,4-diazepines and the influenc e of temperature on the retention. The fact of ''enantiomerization'' o f oxazepam by the chromatographic process on a beta-cyclodextrin colum n is described.