H. Davidowa et al., SLOW AND FAST LATERAL GENICULATE NEURONS ARE DIFFERENTLY INFLUENCED BY ACETYLCHOLINE, Brain research bulletin, 31(5), 1993, pp. 455-461
In rats anesthetized with urethane, potentials of 108 neurons were rec
orded extracellularly in the dorsal part of the lateral geniculate bod
y (dLGB). Neuronal responses to diffuse light stimuli were studied bef
ore and during the iontophoretic application of acetylcholine (ACh). A
lthough individual cells of all groups of functionally different neuro
n types could be influenced by ACh, responses to flashes were most pro
nounced and uniformly enhanced in the groups of SLOW ON-like cells loc
ated in the dorsolateral and caudal parts of the dLGB. The activity in
primary response phases to light flashes increased also in caudally l
ocated SLOW OFF-like cells. In the group of ventromedially located FAS
T OFF-like cells the postinhibitory offdischarge in the response to fl
ash was significantly augmented. Only few cells of FAST ON-like groups
were affected and some of them inhibited by ACh.