We could demonstrate pigment-dispersing hormone immunoreactive (PDHIR)
neurons in the brain and ventral ganglia of the blowfly Phormia terra
enovae. PDHIR neurons were found in the optic lobe. Their processes su
pply the lamina, medulla and lobula complex bilaterally. Large PDHIR c
ell bodies in the protocerebrum have processes in the proto- and trito
cerebrum and axons to the aorta wall and foregut. Eight pairs of PDHIR
neurons are found dorsally and three pairs ventrally in the fused abd
ominal neuromeres; one pair is located ventrally in each of the thorac
ic neuromeres. The ventral abdominal PDHIR neurons are efferents that
innervate the hindgut. PDHIR neurons may play different functional rol
es as neurohormones or neuromodulators in different parts of the nervo
us system and its peripheral targets.