Sixty eyes-30 with severe nonproliferative diabetic retinopathy (NPDR)
and 30 with proliferative diabetic retinopathy (PDR)-underwent argon
laser panretinal photocoagulation (PRP). Static perimetry (Humphrey au
tomated visual field analyzer 630, Threshold Prog Central 30-1 and Per
i 30/60-1) was done 1 day before and 6 weeks after the initial laser t
reatment. One day before treatment, the fields of the NPDR and PDR eye
s differed mainly in the central field affection: the PDR eyes had mor
e localized areas of markedly decreased retinal sensitivity and, there
fore, a higher initial mean deviation value and higher corrected patte
rn standard deviation values. However, peripheral retinal sensitivity
was equally depressed in the NPDR and PDR eyes. Six weeks after treatm
ent, central retinal sensitivity had significantly improved in all of
the eyes, although more so in the eyes with severe NPDR. This study su
ggests that static-perimetry-guided PRP is an effective treatment for
diabetic retinopathy, especially severe NPDR.