Sl. Owens et al., PRELIMINARY-STUDY OF A NEW INTRAOCULAR METHOD IN THE DIAGNOSIS AND TREATMENT OF PROPIONIBACTERIUM ACNES ENDOPHTHALMITIS FOLLOWING CATARACT-EXTRACTION, Ophthalmic surgery, 24(4), 1993, pp. 268-272
Late endophthalmitis, due to Propionibacterium acnes, developed in thr
ee patients following uncomplicated extracapsular cataract extraction
and posterior chamber intraocular lens (PC-IOL) insertion. Cultures fr
om the capsular bag yielded P acnes in all three. With topical anesthe
sia and through an anterior chamber paracentesis, culture specimens we
re taken from and clindamycin irrigated into the capsular bag. Filtere
d 100% oxygen was introduced into the anterior chamber in two; the thi
rd also received an injection of gentamicin and dexamethasone into the
capsular bag. After treatment, two patients received oral antibiotics
; one received hyperbaric oxygen therapy. Visual acuity was improved a
nd inflammation reduced in all three. However, after treatment, ocular
toxic effects due to clindamycin were suspected in one. This approach
offers several clear advantages, including topical anesthesia, outpat
ient management, elimination of the need for vitrectomy, and retention
of the intraocular lens (IOL).