GENETIC-CONTROL OF POPULATION-STRUCTURE IN HETEROGENEOUS STRAINS OF METHICILLIN RESISTANT STAPHYLOCOCCUS-AUREUS

Authors
DELENCASTRE H FIGUEIREDO AMS TOMASZ A
Citation
H. Delencastre et al., GENETIC-CONTROL OF POPULATION-STRUCTURE IN HETEROGENEOUS STRAINS OF METHICILLIN RESISTANT STAPHYLOCOCCUS-AUREUS, European journal of clinical microbiology & infectious diseases, 12, 1993, pp. 13-18
Citations number
9
Journal title
European journal of clinical microbiology & infectious diseases → ACNP
ISSN journal
09349723
Volume
12
Year of publication
1993
Supplement
1
Pages
13 - 18
Database
ISI
SICI code
0934-9723(1993)12:<13:GOPIHS>2.0.ZU;2-N
Abstract
Cultures of heterogeneous strains of methicillin resistant Staphylococ cus aureus are composed of several subpopulations of cells that differ in their level of antibiotic resistance and frequencies. Experimental evidence is presented indicating that the number of these subpopulati ons, their resistance level and the frequency with which they are repr esented in a culture are strain-specific and reproducible with a surpr ising degree of precision from one culture to another. This implies a genetic control of population structure in these bacteria.