SYNTHESIS AND CHARACTERIZATION OF HIGHLY STABLE POLYMER-COATED AMINOSILICA PACKING MATERIAL FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Authors
KUTSUNA H OHTSU Y YAMAGUCHI M
Citation
H. Kutsuna et al., SYNTHESIS AND CHARACTERIZATION OF HIGHLY STABLE POLYMER-COATED AMINOSILICA PACKING MATERIAL FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography, 635(2), 1993, pp. 187-193
Citations number
16
Journal title
Journal of chromatography → ACNP
Volume
635
Issue
2
Year of publication
1993
Pages
187 - 193
Database
ISI
SICI code
Abstract
A synthetic procedure leading to an amino-bonded stationary phase for high-performance liquid chromatography was developed. The silica surfa ce was first coated with a silicone polymer monolayer and an amino fun ctionality was subsequently attached to the polymer layer. The polymer -coated amino-bonded phase showed improved stability and separation in the analysis of carbohydrates and nucleotides over conventional amino propylsilylated silicas.