EPIDERMAL GROWTH-FACTOR IN THE TOPICAL TREATMENT OF TRAUMATIC CORNEALULCERS

The tolerability and efficacy of epidermal growth factor (EGF) in the topical treatment of traumatic corneal ulcers have been evaluated in a double-blind, placebo-controlled, randomized study in two groups of p atients. The time required for complete reepithelialization of the cor nea was recorded, and the data obtained were analyzed statistically. I n the EGF group the reepithelialization was significantly faster than in the control group. Tolerability of EGF was always excellent. These results indicate that EGF is safe and effective in reducing the healin g time in the management of superficial corneal lesions.