The results of treatment in 74 patients treated in 1978-1990 for adeno
carcinoma of the esophagus were retrospectively analyzed. The overall
five-year survival was 7.8%, the median survival 10.0 months. Eighteen
patients underwent a resection, in 13 patients with curative and in 5
patients with palliative intent. The median survival for these groups
was 13.5 and 5.8 months, respectively. Thirty-one patients were irrad
iated. The response rate according to the WHO passage score was 79%. T
he median duration of response and survival was 6.0 and 9.5 months, re
spectively. Twenty patients were given palliative treatment, in the fo
rm of an endoprosthesis (10 patients), an endoprosthesis with chemothe
rapy (4 patients) or only chemotherapy (6 patients). The median durati
on of survival of patients in the palliative group was 6.5 months. The
data are discussed in relation to results of treatment described in t
he literature.