THE INFUSION OF ANTI-RHO-(D) OPSONIZED ERYTHROCYTES MAY BE USEFUL IN THE TREATMENT OF PATIENTS, SPLENECTOMIZED OR NOT, WITH CHRONIC, REFRACTORY AUTOIMMUNE THROMBOCYTOPENIC PURPURA - A PROSPECTIVE-STUDY

Authors
RUIZARGUELLES GJ APREZAMOLINA MG PEREZROMANO B RUIZARGUELLES A
Citation
Gj. Ruizarguelles et al., THE INFUSION OF ANTI-RHO-(D) OPSONIZED ERYTHROCYTES MAY BE USEFUL IN THE TREATMENT OF PATIENTS, SPLENECTOMIZED OR NOT, WITH CHRONIC, REFRACTORY AUTOIMMUNE THROMBOCYTOPENIC PURPURA - A PROSPECTIVE-STUDY, American journal of hematology, 43(1), 1993, pp. 72-73
Citations number
8
Journal title
American journal of hematology → ACNP
ISSN journal
03618609
Volume
43
Issue
1
Year of publication
1993
Pages
72 - 73
Database
ISI
SICI code
0361-8609(1993)43:1<72:TIOAOE>2.0.ZU;2-0
Abstract
Six patients with chronic refractory autoimmune thrombocytopenic purpu ra (ATP) were treated with five doses of autologous red blood cells (R BCs) opsonized ex vivo with anti-RhO-(D) IgG. Increases in platelet co unts were observed in all cases; complete responses requiring no furth er treatment-for periods of 8-72 months-were recorded in four patients , three of them splenectomized. The cost of the procedure was signific antly lower than other ''Fc receptor (FcR) blockade'' treatments.