Mv. Kulkarni et G. Viswanathan, PLASMA-LIPOPROTEIN (A) LEVELS SHOWING AGE-RELATED-CHANGES IN DIABETICAND HYPERTENSIVE INDIVIDUALS, Journal of clinical biochemistry and nutrition, 21(2), 1996, pp. 151-155
We measured plasma levels of lipoprotein (a) [Lp(a)] in 117 individual
s. A highly significant relationship between Lp(a) and increasing age
was found in hypertensive patients but not in normals. These patients
also showed marked variation in both total cholesterol and low-density
lipoprotein (LDL)-cholesterol levels. In diabetic subjects, despite t
he significant elevation in TG and very low-density lipoprotein-choles
terol, the increase in Lp(a) concentration was not significant, probab
ly due to a more rapid clearance of triglyceride rich particle apo (a)
of Lp(a) compared to the slower apo (a) catabolism in the LDL density
range.